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Structured Review

Sangon Biotech oligonucleotide strand
Oligonucleotide Strand, supplied by Sangon Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/oligonucleotides/oligonucleotide+primers/pmc13191104-267-5-74
Average 86 stars, based on 1 article reviews
oligonucleotide strand - by Bioz Stars, 2026-09
86/100 stars

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Related Articles

Purification:

Article Title: Visualizing cellular G-quadruplexes with a bioinspired chemiluminescent probe.
Article Snippet: .. All oligonucleotides (sequences given in Supplementary Table S1 ) used in this study were purified by HPLC and purchased from Sangon Biotech (China). ..

Article Title: Characteristics of specific DNA junction motifs inspired by natural RNA motifs.
Article Snippet: DNA junction motifs play critical roles in biological activities and precise DNA nanoconstruction.. However, the relationship between the sequence of junction motifs and their structural characteristics remains unclear.. Herein we designed a specific DNA three-way junction (D3) motif and a DNA kink-turn (DK) motif by mimicking natural RNA motifs.

High Performance Liquid Chromatography:

Article Title: Visualizing cellular G-quadruplexes with a bioinspired chemiluminescent probe.
Article Snippet: .. All oligonucleotides (sequences given in Supplementary Table S1 ) used in this study were purified by HPLC and purchased from Sangon Biotech (China). ..

Article Title: FEN1-Gated Rolling Circle Amplification Achieves Single-Base Mismatch Discrimination for Breast Cancer Biomarker Analysis.
Article Snippet: Rolling circle amplification (RCA) is a powerful isothermal nucleic acid amplification technique, yet its specificity is often compromised because padlock probes can be circularized even with imperfectly matched targets, leading to false-positive signals.. Herein, we report a strand displacement-assisted FEN1 cleavage strategy to substantially improve the specificity of RCA.. A dumbbell-shaped padlock probe is designed to generate dual 5′ flaps only upon perfect hybridization with the target.

Article Title: Multimodal imaging of gene expression, morphology, and activity of the same neuron.
Article Snippet: In brief This study establishes an imaging-based multimodal characterization (IMC) platform to link in vivo activity, wholebrain morphology, and spatial gene expression in the same cortical projection neurons.. Applied to the mouse visual cortex, IMC reveals complementary morphological and molecular predictors of visual responses, identifies a neuronal subtype defined by trimodal profiling, and provides a ground-truth resource for multimodal integration.

Article Title: Development of a dCas13a/crRNA-Linked Immunosorbent Mimic Assay (dCLIMA) for Sensitive and Accurate Circular RNA Analysis in Lung Cancer-Derived Circulating Tumor Cells.
Article Snippet: Circular RNAs (circRNAs) are emerging as promising biomarkers in liquid biopsy, yet their accurate detection in circulating tumor cells remains challenging due to low abundance and interference from linear RNA counterparts.. Here, we develop a dCas13a/crRNA-Linked Immunosorbent Mimic Assay (dCLIMA) for sensitive and specific colorimetric detection of circRNAs.. The dCas13a/crRNA complex immobilized on a microplate specifically captures target circRNAs via their back-splicing junction (BSJ) region, eliminating linear RNA interference.

Article Title: Characteristics of specific DNA junction motifs inspired by natural RNA motifs.
Article Snippet: DNA junction motifs play critical roles in biological activities and precise DNA nanoconstruction.. However, the relationship between the sequence of junction motifs and their structural characteristics remains unclear.. Herein we designed a specific DNA three-way junction (D3) motif and a DNA kink-turn (DK) motif by mimicking natural RNA motifs.

Conjugation Assay:

Article Title: FEN1-Gated Rolling Circle Amplification Achieves Single-Base Mismatch Discrimination for Breast Cancer Biomarker Analysis.
Article Snippet: Rolling circle amplification (RCA) is a powerful isothermal nucleic acid amplification technique, yet its specificity is often compromised because padlock probes can be circularized even with imperfectly matched targets, leading to false-positive signals.. Herein, we report a strand displacement-assisted FEN1 cleavage strategy to substantially improve the specificity of RCA.. A dumbbell-shaped padlock probe is designed to generate dual 5′ flaps only upon perfect hybridization with the target.

Synthesized:

Article Title: FEN1-Gated Rolling Circle Amplification Achieves Single-Base Mismatch Discrimination for Breast Cancer Biomarker Analysis.
Article Snippet: Rolling circle amplification (RCA) is a powerful isothermal nucleic acid amplification technique, yet its specificity is often compromised because padlock probes can be circularized even with imperfectly matched targets, leading to false-positive signals.. Herein, we report a strand displacement-assisted FEN1 cleavage strategy to substantially improve the specificity of RCA.. A dumbbell-shaped padlock probe is designed to generate dual 5′ flaps only upon perfect hybridization with the target.

Article Title: Multimodal imaging of gene expression, morphology, and activity of the same neuron.
Article Snippet: In brief This study establishes an imaging-based multimodal characterization (IMC) platform to link in vivo activity, wholebrain morphology, and spatial gene expression in the same cortical projection neurons.. Applied to the mouse visual cortex, IMC reveals complementary morphological and molecular predictors of visual responses, identifies a neuronal subtype defined by trimodal profiling, and provides a ground-truth resource for multimodal integration.

Article Title: Development of a dCas13a/crRNA-Linked Immunosorbent Mimic Assay (dCLIMA) for Sensitive and Accurate Circular RNA Analysis in Lung Cancer-Derived Circulating Tumor Cells.
Article Snippet: Circular RNAs (circRNAs) are emerging as promising biomarkers in liquid biopsy, yet their accurate detection in circulating tumor cells remains challenging due to low abundance and interference from linear RNA counterparts.. Here, we develop a dCas13a/crRNA-Linked Immunosorbent Mimic Assay (dCLIMA) for sensitive and specific colorimetric detection of circRNAs.. The dCas13a/crRNA complex immobilized on a microplate specifically captures target circRNAs via their back-splicing junction (BSJ) region, eliminating linear RNA interference.

Article Title: Acceleration of DNA reactions on the algae-based microrobots.
Article Snippet: .. All used oligonucleotides (Table S1) were synthesized by 129 Sangon Biotech Co., Ltd. Shanghai. ..

other:

Article Title: An Autocatalytic Molecular Sensor Enables Rapid, Sensitive, and One-Pot Detection of Nucleic Acids.
Article Snippet: Circulating nucleic acids are emerging disease markers whose clinical applications are hindered by the lack of rapid, sensitive, convenient, and cost-effective detection assays.. Inspired by the natural replication of virus, here, we developed a biomimetic one-step, one-pot, isothermal detection assay named RAPID to realize rapid and sensitive detection of nucleic acids with minimal reliance on instruments.. The core element of RAPID is an autocatalytic molecular sensor that exploits the viral replication endonuclease of duck circovirus (i.e., DCV) to transform rolling circle amplification (RCA) from linear to exponential.



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